The Pasteur Center of Cameroon recently hosted the 76th edition of the Pasteur Wednesdays, focused on the theme “Biomarkers in Oncology: From Detection to Therapeutic Monitoring.” This scientific meeting brought together a diverse audience of students, clinicians, biologists, and decision-makers, highlighting the growing interest in cancers, complex diseases that require a truly multidisciplinary approach.

Four experts provided complementary insights into the current issues surrounding biomarkers. Dr. Edmond BODO, a pathologist at the Pasteur Center of Cameroon, recalled that a biomarker is a measurable and objective indicator that allows the characterization of normal or pathological biological processes. He presented the main categories of biomarkers used in anatomy and cytopathology, including molecular biomarkers (genome, RNA, proteins), cellular (cell types or immune profiles), biochemical (enzymes, metabolites, cytokines), and physiological (blood pressure, heart rate).

In oncology, these biomarkers play a crucial role, both in aiding diagnosis and in assessing prognosis, by helping to estimate the aggressiveness of tumors. They also have essential predictive value, assisting in anticipating patients’ sensitivity or resistance to treatments.

Bringing a clinical perspective, Dr. Lionel BALLA, oncologist at Yaoundé General Hospital, emphasized that, despite still limited local availability, biomarkers offer promising prospects. They facilitate ongoing monitoring of the disease and represent a real hope for cancer patients, particularly through early detection and the development of targeted and personalized therapies.

Dr. Nickele EMASSI, for his part, highlighted the biomarkers commonly used in biochemical analyses conducted at the Pasteur Center in Cameroon, thus illustrating their practical application in daily diagnostic practice. Meanwhile, Dr. Imad ADOUÉ, Scientific Director at MEDDIF, presented innovative digital tools developed to complement the diagnosis of certain pathologies using biomarkers.

Moderated by Professor Joseph Marie MENDIMI, technical advisor at the Ministry of Public Health, the discussions allowed participants, particularly health professionals and students, to update their knowledge and better understand the current and future challenges related to the use of biomarkers in the health sector.